This work discusses atrophy in the medial temporal lobe during the progression of early Alzheimer's disease.
This work discusses time dependent models of shape changes to study neurodegeneration.
We developed optimal control formulations for parameterizing deformations and features described at multiple scales. This work is contributing to brain atlasing initatives for microscopy images.
We design diffeomorphic techniques to estimate unobserved data between sparsely sampled slices in cardiac MRI.
We derived the Cramer Rau bound for estimating volume changes from deformable image registration, which is a lower bound on the variance of an estimator. We demonstrated its implications for image registration performance in asymmetric methods versus symmetric methods, the former generally performing better.