This work examines the effect of lithium treatment in bipolar disorder on the structure of the hippocampus and amygdala.
Cloud based processing, atlas mapping, and visualization of massive neuroimages for multiple species and modalities.
This work discusses atrophy in the medial temporal lobe during the progression of early Alzheimer's disease.
This work discusses the association between visbular function (measured through cervical vestibular-evoked myogenic potential) and brain structures of interest using imaging data from the Baltimore Longitudinal Study of Aging.
This work discusses time dependent models of shape changes to study neurodegeneration.
We developed optimal control formulations for parameterizing deformations and features described at multiple scales. This work is contributing to brain atlasing initatives for microscopy images.
This work discusses the challenges of 3D printing hippocampi from annotated post mortem MRI. This work will help visualize subtle changes to complex anatomy during the disease.
We developed a generative algorithm for registration of micron resolution serial section microscopy images to the Allen reference atlas.
We design diffeomorphic techniques to estimate unobserved data between sparsely sampled slices in cardiac MRI.
We derived the Cramer Rau bound for estimating volume changes from deformable image registration, which is a lower bound on the variance of an estimator. We demonstrated its implications for image registration performance in asymmetric methods versus symmetric methods, the former generally performing better.