Molecular Computational Anatomy: Unifying the Particle to Tissue Continuum via Measure Representations of the Brain

We formalized the mathematical representation of imaging data features from the molecular to anatomical scales, and showed analysis for several examples including deposition of pathology in Alzheimer's disease.

Coarse-to-Fine Hamiltonian Dynamics of Hierarchical Flows in Computational Anatomy

We developed optimal control formulations for parameterizing deformations and features described at multiple scales. This work is contributing to brain atlasing initatives for microscopy images.