Histological validation of human post mortem amygdala DTI

Analysis of fiber orientation in 3D MRI and myelin stained 2D sections, poster presentation at SFN.

B. Gray, C. Mezias, S. Savoia, R. Coronado-Leija, D. S. Novikov, E. Fieremans, J. Zhang, D. Nauen, P. P. Mitra, and D. J. Tward, in 2022 Soceity for Neuroscience Annual Meeting.
Solving the where problem in neuroanatomy: a generative framework with learned mappings to register multimodal, incomplete data into a reference brain

We developed a generative algorithm for registration of micron resolution serial section microscopy images to the Allen reference atlas.

D. J. Tward, X. Li, B. Huo, B. C. Lee, M. Miller, and P. P. Mitra, in bioRxiv.
Estimating diffeomorphic mappings between templates and noisy data: Variance bounds on the estimated canonical volume form

We derived the Cramer Rau bound for estimating volume changes from deformable image registration, which is a lower bound on the variance of an estimator. We demonstrated its implications for image registration performance in asymmetric methods versus symmetric methods, the former generally performing better.

D. J. Tward, P. P. Mitra, and M. I. Miller, in Quarterly of applied mathematics.
On variational solutions for whole brain serial-section histology using the computational anatomy random orbit model
B. C. Lee, D. J. Tward, P. P. Mitra, and M. I. Miller, in arXiv preprint arXiv:1802.03453.