An optimized tissue clearing protocol for rat brain labeling, imaging, and high throughput analysis

Preliminary work analizing large rat brain images using the iDISCO brain clearing protocol.

A. Branch, D. J. Tward, A. C. Kolstad, V. Pulyadi, J. T. Vogelstein, Z. Wu, and M. Gallagher, in bioRxiv.
Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors
A. Graves, R. Roth, H. Tan, Q. Zhu, A. Bygrave, E. Lopez-Ortega, A. Spiegel, I. Hong, R. Johnson, J. Vogelstein, and others, in bioRxiv.
Solving the where problem in neuroanatomy: a generative framework with learned mappings to register multimodal, incomplete data into a reference brain

We developed a generative algorithm for registration of micron resolution serial section microscopy images to the Allen reference atlas.

D. J. Tward, X. Li, B. Huo, B. C. Lee, M. Miller, and P. P. Mitra, in bioRxiv.
An optimized protocol for iDISCO+ rat brain clearing, imaging, and analysis
A. Branch, D. Tward, J. T. Vogelstein, Z. Wu, and M. Gallagher, in bioRxiv.
EM-LDDMM for 3D to 2D registration
D. Tward, and M. Miller, in BioRxiv.