A 7 Tesla Amygdalar-Hippocampal Shape Analysis of Lithium Response in Bipolar Disorder

This work examines the effect of lithium treatment in bipolar disorder on the structure of the hippocampus and amygdala.

T. L. Athey, C. Ceritoglu, D. J. Tward, K. S. Kutten, J. R. Depaulo, K. Glazer, F. S. Goes, J. R. Kelsoe, F. Mondimore, C. M. Nievergelt, and others, in Frontiers in Psychiatry.
CloudReg: Automatic Terabyte-Scale Cross-Modal Brain Volume Registration

Cloud based processing, atlas mapping, and visualization of massive neuroimages for multiple species and modalities.

V. Chandrashekhar, D. J. Tward, D. G. Crowley, A. K. Crow, M. A. Wright, B. Y. Hsueh, F. Gore, T. A. Machado, A. Branch, J. S. Rosenblum, and others, in bioRxiv.
Toward Community-Driven Big Open Brain Science: Open Big Data and Tools for Structure, Function, and Genetics

As acquiring bigger data becomes easier in experimental brain science, com-putational and statistical brain science must achieve similar advances to fullycapitalize on these data. Tackling these problems will benefit from a moreexplicit and concerted effort to work together. Specifically, brain sciencecan be further democratized by harnessing the power of community-driven tools, which both are built by and benefit from many different people with different backgroundsand expertise. This perspective can be applied across modalities and scales and enables collabora-tions across previously siloed communities.

A. S. Charles, B. Falk, N. Turner, T. D. Pereira, D. Tward, B. D. Pedigo, J. Chung, R. Burns, S. S. Ghosh, J. M. Kebschull, and others, in Annual Review of Neuroscience.
Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptors
A. Graves, R. Roth, H. Tan, Q. Zhu, A. Bygrave, E. Lopez-Ortega, A. Spiegel, I. Hong, R. Johnson, J. Vogelstein, and others, in bioRxiv.
Cortical thickness atrophy in the transentorhinal cortex in mild cognitive impairment
S. Kulason, D. J. Tward, T. Brown, C. S. Sicat, C. Liu, J. T. Ratnanather, L. Younes, A. Bakker, M. Gallagher, M. Albert, and others, in NeuroImage: Clinical.
A Community-Developed Open-Source Computational Ecosystem for Big Neuro Data
R. Burns, E. Perlman, A. Baden, W. G. Roncal, B. Falk, V. Chandrashekhar, F. Collman, S. Seshamani, J. Patsolic, K. Lillaney, and others, in arXiv preprint arXiv:1804.02835.
NeuroStorm: Accelerating Brain Science Discovery in the Cloud
G. Kiar, R. J. Anderson, A. Baden, A. Badea, E. W. Bridgeford, A. Champion, V. Chandrashekhar, F. Collman, B. Duderstadt, A. C. Evans, and others, in arXiv preprint arXiv:1803.03367.
A community-developed open-source computational ecosystem for big neuro data
J. T. Vogelstein, E. Perlman, B. Falk, A. Baden, W. G. Roncal, V. Chandrashekhar, F. Collman, S. Seshamani, J. L. Patsolic, K. Lillaney, and others, in Nature methods.
Entorhinal and transentorhinal atrophy in mild cognitive impairment using longitudinal diffeomorphometry
D. J. Tward, C. S. Sicat, T. Brown, A. Bakker, M. Gallagher, M. Albert, M. Miller, Alzheimer's Disease Neuroimaging Initiative, and others, in Alzheimer's \& Dementia: Diagnosis, Assessment \& Disease Monitoring.
Singular geodesic coordinates for representing diffeomorphic maps in computational anatomy, with application to the morphometry of early Alzheimer's disease in the medial temporal lobe
D. J. Tward, and others, in Johns Hopkins University.

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